彭政

职称：校聘副研究员

学历/学位：研究生/博士

电话：15852838801

电子邮箱：zhengpeng@jiangnan.edu.cn

研究领域：

主要从事蛋白质工程和合成生物学领域的基础和应用研究，利用蛋白质工程和合成生物学技术实现功能蛋白（酶、肽和蛋白材料等）的定向设计及高效表达，开发功能蛋白在生物质资源增值、食品生物合成以及环境修复等领域的应用。近年来在领域权威期刊上发表SCI论文30余篇，申请/授权发明专利15件，主持国家自然科学基金、国家重点研发计划等纵向科研项目4项，入选江苏省卓越博士后计划（2022）。

国际国内学术组织任职情况:

Frontiers In Synthetic Biology, Review Editor (2023.11-)

学习工作经历

2023.12-至今，江南大学未来食品科学中心/生物工程学院校聘副研究员

2021.11-2023.11，江南大学未来食品科学中心博士后/助理研究员

2016.09-2021.01，江南大学发酵工程专业博士

一、论文（论著）发表情况

代表性论文：

1. 1. Yang Yuan,Zheng Peng*, Xinyi Jiang, Qi Zhu, Rongping Chen, Wenzhen Wang, Anxing Liu, Chengjian Wu, Chunhua Ma, Juan Zhang*. Metabolomics analysis of flavor differences in Shuixian (Camellia sinensis) tea from different production regions and their microbial associations.Food Chemistry, 2024,443, 138542.

2. 2.Zheng Peng, Shuai Luo, Dandan Zhao, Juan Zhang*. Biosynthetic melanin with excellent performance can be used for heavy metal adsorption.Journal of Cleaner Production, 2023, 385: 135655.

3. 3.Zheng Peng, Dandan Zhao, Jun Fang, Jian Chen and Juan Zhang*. Biosynthetic Amyloid Fibril CsgA–Fe₃O₄Composites for Sustainable Removal of Heavy Metals from Water.Separation and Purification Technology, 2023, 329, 125191.

4. 4.Zheng Peng, Ran Wang, Xiaofeng Xia*, Juan Zhang*. Engineered acetaldehyde dehydrogenase for the efficient degradation of acetaldehyde.Journal of Environmental Management, 2023, 331: 117258.

5. 5.Zheng Peng, Mengni He, Xinyu Yang, Juan Zhang*. Discovery and characterization of a novel bacteriocin HA2-5 that strongly inhibitsPropionibacterium acnes.Journal of Agricultural and Food Chemistry, 2023, 71(34), 12741–12748.

6. 6. Xiwen Chen^#,Zheng Peng^#*, Xiaomei Ji and Juan Zhang*. Reducing cellular autolysis ofBacillus subtilisto improve keratinase production.ACS Synthetic Biology, 2023, 12(10): 3106–3113.

7. 7.Zheng Peng, Zhoudi Miao, Xiaomei Ji, Guoqiang Zhang, Juan Zhang*. Engineering flexible loops to enhance thermal stability of keratinase for efficient keratin degradation.Science of the Total Environment, 2022, 845:157161.

8. 8.Zheng Peng, Xinzhe Mao, Wanmeng Mu, Guocheng Du, Jian Chen, Juan Zhang*. Modifying the Substrate Specificity of Keratinase for Industrial Dehairing to Replace Lime-Sulfide.ACS Sustainable Chemistry & Engineering, 2022, 10(20): 6863-6870.

9. 9. Jun Fang, Guanyu Zhou, Xiaomei Ji, Guoqiang Zhang,Zheng Peng*, Juan Zhang*. Design of 5'-UTR to enhance keratinase activity inBacillus subtilis.Fermentation, 2022, 8(9), 426.

10. 10.Zheng Peng, Peng Xu, Yang Song, Guocheng Du, Juan Zhang* and Jian Chen*. Cysteine-mediated cyclic metabolism drives the microbial degradation of keratin.ACS Sustainable Chemistry & Engineering,2021, 9(29): 9861-9870.

11. 11.Zheng Peng, Juan Zhang*, Yang Song, Rong Guo, Guocheng Du and Jian Chen*. Engineered pro-peptide enhances the catalytic activity of keratinase to improve the conversion ability of feather waste.Biotechnology and Bioengineering, 2021, 118(7): 2559-2571.

12. 12.Zheng Peng, Xinzhe Mao, Juan Zhang*, Guocheng Du and Jian Chen*. Biotransformation of keratin waste to amino acids and active peptides based on cell-free catalysis.Biotechnology for Biofuels, 2020, 13: 61.

13. 13.Zheng Peng, Juan Zhang*, Guocheng Du and Jian Chen*. Keratin Waste Recycling Based on Microbial Degradation: Mechanisms and Prospects.ACS Sustainable Chemistry & Engineering, 2019, 7(11): 9727-9736.

14. 14.Zheng Peng, Xinzhe Mao, Juan Zhang*, Guocheng Du and Jian Chen*. Effective biodegradation of chicken feather waste by co-cultivation of keratinase producing strains.Microbial Cell Factories, 2019, 18(1): 84.

15. 15. Xinyu Yang^#,Zheng Peng^#, Mengni He, Zhibin Li, Guihua Fu, Shaolei Li, Juan Zhang*. Screening, probiotic properties, and inhibition mechanism of aLactobacillus antagonistictoListeria monocytogenes.Science of The Total Environment, 2023, 906, 167587.

16. 16. Dandan Zhao^#,Zheng Peng^#, Jun Fang, Zhen Fang*, Juan Zhang*. Programmable and low-cost biohybrid membrane for efficient heavy metal removal from water.Separation and Purification Technology, 2023, 306, 122751.

17. 17. Xiaomei Ji^#,Zheng Peng^#, Jie Song, Guoqiang Zhang, and Juan Zhang*. Fusion of Substrate-Binding Domains Enhances the Catalytic Capacity of Keratinases and Promotes Enzymatic Conversion of Feather Waste.Journal of Agricultural and Food Chemistry, 2023, 71(30): 11579–11586.

18. 18. Xiaoxue Yang^#,Zheng Peng^#, Qi Zhu, Chengcong Chen, Jiheng Liu, Songtao Fu, Juan Zhang*. Analysis of Tieguanyin aged aroma compounds and their correlation with microbial communities based on multi-omics analysis.LWT - Food Science & Technology, 2023, 185: 115205.

    二、科研项目

19. 1.国家自然科学基金青年项目(22208125) 2023.01-2025.12,项目负责人

20. 2.国家重点研发计划(2022YFD2101201) 2022.11-2027.10,子课题负责人

21. 3.江苏省自然科学基金青年项目(BK20221084) 2022.07-2025.06,项目负责人

22. 4.南平市资源化学产业科技创新联合资助项目(N2022Z003) 2023.01-2025.06,项目负责人

23. 5.国家重点研发计划(2022YFD2101402) 2022.11-2026.10,参与

24. 6.国家重点研发计划(2021YFA0911501) 2021.12-2026.11,参与

三、科研成果及奖励

1. 1.江苏省卓越博士后计划(2022ZB497)江苏省人力资源和社会保障厅(2022年)

四、所获专利

1. 1. Zhang Juan,Peng Zheng, Chen Jian, Du Guocheng, Mao Xinzhe, Zhou Hengrui. RecombinantBacillus SubtilisEngineered Bacterium Capable of Efficiently Expressing Keratinase.专利号：US 11384394 B2

2. 2.张娟，彭政，宋婕，陈坚，吉晓梅，堵国成，李江华.一种具有底物选择性的角蛋白酶突变体及其应用.专利号:2023117300290

3. 3.张娟，彭政，陈希文，陈坚，堵国成，李江华.一种蛋白酶表达水平提高的底盘细胞.专利号:202310929472.4

4. 4.张娟，彭政，吉晓梅，陈坚，堵国成，李江华.一种利用角蛋白酶水解玉米黄粉醇溶蛋白的方法.专利号:2023107480117

5. 5.张娟，彭政，宋婕，陈坚，堵国成，李江华，吉晓梅.一种通过融合底物结合功能域提升水解能力的角蛋白酶突变体.专利号: 2023100903337

6. 6.张娟，彭政，吉晓梅，陈坚，堵国成，李江华.一种无胶原蛋白水解活性的角蛋白酶突变体.专利号:202211539892.3

7. 7.张娟，彭政，杨欣宇，陈坚，吴巧茵，堵国成，李江华.一株可广谱抑制食品腐败菌的乳酸菌及其应用.专利号: ZL 202210651979.3

8. 8.张娟，彭政，陈坚，堵国成.一种前导肽突变体及其在角蛋白酶生产中的应用.专利号: ZL 201911153529.6

9. 9.张娟，陈坚，彭政，堵国成，任春慧，范旭程.一种利用角蛋白酶生产菌株高效降解羽毛的方法.专利号: ZL 201711236769.3

以上资料更新时间截止：2024年1月